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up: modkit parameters to improve modification data analysis

João Henrique Chrusciel requested to merge dev/nxtcfg into main
  • changed modkit extract full to modkit extract calls for testing (future updates will contain a new modified modkit extract full);
  • implemented reference FASTA file in modkit extract calls;
  • updated modkit.yaml with path to reference file used in modkit;
  • implemented region delimiter to mitochondrial DNA using --region MT;
  • implemented a filter-threshold of 0.9 for all bases;
  • implemented bgzf compression of calls.tsv to improve storage management;
  • implemented modkit sample-probs to analyse distribution of bases (cannonicals and modified) across the samples;
  • added 6mA in nextflow.config to be basecalled concurrently with 5mC_5hmC.
Edited by João Henrique Chrusciel

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