up: modkit parameters to improve modification data analysis
- changed
modkit extract full
tomodkit extract calls
for testing (future updates will contain a new modifiedmodkit extract full
); - implemented reference FASTA file in
modkit extract calls
; - updated
modkit.yaml
with path to reference file used in modkit; - implemented region delimiter to mitochondrial DNA using
--region MT
; - implemented a filter-threshold of 0.9 for all bases;
- implemented bgzf compression of calls.tsv to improve storage management;
- implemented
modkit sample-probs
to analyse distribution of bases (cannonicals and modified) across the samples; - added 6mA in
nextflow.config
to be basecalled concurrently with 5mC_5hmC.
Edited by João Henrique Chrusciel