diff --git a/README.md b/README.md
index 5219af899716c193a2d76ea7b99f23939feb2cbc..8e460b488a18b5582418ac8d49f95268422eee17 100755
--- a/README.md
+++ b/README.md
@@ -321,6 +321,39 @@ Alternatively, you can  make use of an existing [configuration profile](#config-
 nextflow ./src/main.nf -profile human_blood_basecall
 ```
 
+### Slurm script
+
+The pipeline can be executed in an HPC environment using [Slurm](https://slurm.schedmd.com/). A job submission template for basecalling with the `human_blood_basecall` profile is provided below.
+
+1. Create a shell script:
+
+    ```sh
+    nano hb_basecall.sh
+    ```
+
+1. Add and edit the following template:
+
+    ```sh
+    #!/bin/sh
+    #SBATCH --time 1-0
+    #SBATCH --error basecall_err.log
+    #SBATCH --output basecall_out.log
+    #SBATCH --mem 24G
+    #SBATCH --cpus-per-task 12
+    #SBATCH --gpus 3
+    srun nextflow run ./src/main.nf \
+        -profile human_blood_basecall \
+        --basecall_mods "5mC_5hmC,6mA"
+    ```
+
+1. Make the file executable and submit the job to the queue:
+
+    ```sh
+    chmod +x hb_basecall.sh
+    sbatch hb_basecall.sh
+    squeue
+    ```
+
 [top](#table-of-contents)
 
 ## Useful links